The loss of Asia Minor is often seen as the most decisive factor in the fall of the Byzantine Empire. Asia Minor was the territorial core of the empire during the Middle Byzantine Era. It was a wealthy and populous country of many millions of inhabitants, the main source of resources, raw materials, human resources, employees and soldiers for the Byzantine Empire. Its loss was, indeed, a major cause for the collapse of the Empire. However, this collapse was due to higher and wider political, social, economic, military, religious, ethnological and other negative parameters which in the first place led to the fall of Byzantine Asia Minor and then to the fall of the other imperial territories and eventually of the capital itself. More